Christelle Glangetas
Institut des Maladies
Neurodégénératives, UMR 5293 CNRS, Université de Bordeaux
Title
Insula and social behavior
Abstract
The Insula, which is known for its involvement in multisensory integration and socio-emotional processing, has a particularly robust, yet understudied, connection with its contralateral counterpart. In my recent study, I investigated the functional relevance of Insula-to-Insula (InsulaIns) communication in modulating social behaviour and anxiety in mice. To achieve this, we employed a multidisciplinary approach, combining viral tracer neuroanatomy, ex vivo and in vivo electrophysiology, fiber photometry and targeted neural circuit manipulation. During my presentation, I will discuss how we discovered that InsulaIns neurons are crucial for social discrimination following acute social isolation in mice. Our findings shed new light on the role of insular interhemispheric communication in social and emotional processing.
Biosketch
Christelle Glangetas is a senior neuroscientist working at the Institute of Neurodegenerative Diseases in Bordeaux. She is also a co-organiser of the Brain-Body conference.
She obtained a PhD in Neurosciences at the University of Bordeaux in 2014, where she investigated the role of neuronal plasticity in anxiety control. She moved to Switzerland to the team of Camilla Bellone as a postdoctoral researcher, where she worked on motor and anxiety circuits in physiopathological conditions (Huntington’s disease, Autism Spectrum Disorders). Since 2018, she has joined the team of Jérôme Baufreton and François Georges at the Institute of Neurodegenerative Diseases to understand how the brain shapes emotional behaviors.